PUBLICATION LIST

Papers published in peer reviewed journals

Edvinsson L, Haanes KA. Views on migraine pathophysiology: Where does it start? Neurol Clin Neurosci 2019; online first  

 

Edvinsson JCA, Warfvinge K, Krause DN, Blixt FW, Sheykhzade M, Edvinsson L, Haanes KA. C-fibers may modulate adjacent Adelta-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system. J Headache Pain 2019; 20(1): 105

 

Grell AS, Haanes KA, Johansson SE, Edvinsson L, Sams A Fremanezumab inhibits vasodilatory effects of CGRP and capsaicin in rat cerebral artery - Potential role in conditions of severe vasoconstriction. Eur J Pharmacol (2019) Epub ahead of print, DOI: 1016/j.ejphar.2019.172726

Hougaard A, Younis S, Iljazi A, Haanes KA, Lindberg U, Vestergaard MB, Amin FM, Sugimoto K, Kruse LS, Ayata C, Ashina M Cerebrovascular effects of endothelin-1 investigated using high-resolution magnetic resonance imaging in healthy volunteers. J Cereb Blood Flow Metab (2019) Epub ahead of print, DOI:10.1177/0271678X19874295

Christensen ST, Johansson SE, Warfvinge K, Braun T, Boettger T, Edvinsson L, Haanes KA Exploration of physiological and pathophysiological implications of miRNA-143 and miRNA-145 in cerebral arteries. J Cardiovasc Pharmacol (2019) Epub ahead of print, DOI:10.1097/FJC.0000000000000735

Rubio-Beltran E, Labastida-Ramirez A, Haanes KA, van den Bogaerdt A, Bogers AJJC, Zanelli E, Meeus L, Danser AHJ, Gralinski MR, Senese PB, Johnson KW, Kovalchin J, Villalon CM, MaassenVanDenBrink A Characterization of binding, functional activity and contractile responses of the selective 5-HT1F receptor agonist lasmiditan. Br J Pharmacol (2019). Epub ahead of print, DOI:10.1111/bph.14832

Christensen ST, Haanes KA, Spray S, Grell AS, Warfvinge K, Edvinsson L, Johansson SE.Pre-clinical effects of highly potent MEK1/2 inhibitors on rat cerebral vasculature after organ culture and subarachnoid haemorrhage. Clin Sci (Lond) (2019) 133: 1797-1811. DOI:10.1042/CS20190636

Ohlsson L, Haanes KA, Kronvall E, Xu C, Snellman J, Edvinsson L. Erenumab (AMG 334), a monoclonal antagonist antibody against the canonical CGRP receptor, does not impair vasodilatory or contractile responses to other vasoactive agents in human isolated cranial arteries. Cephalalgia (2019) Epub ahead of print, DOI:10.1177/0333102419867282

Rubio-Beltran E, Labastida-Ramirez A, Haanes KA, van den Bogaerdt A, Bogers AJ, Dirven C, Danser AJ, Xu C, Snellman J, MaassenVanDenBrink A. Characterisation of vasodilatory responses in the presence of the CGRP receptor antibody erenumab in human isolated arteries. Cephalalgia (2019) Epub ahead of print, DOI:10.1177/0333102419863027.

Christensen ST, Grell AS, Johansson SE, Andersson CM, Edvinsson L, Haanes KA Synergistic effects of a cremophor EL drug delivery system and its U0126 cargo in an ex vivo model. Drug Deliv (2019) 26: 680-688. DOI:10.1080/10717544.2019.1636421

Edvinsson L, Haanes KA, Warfvinge K Does inflammation have a role in migraine? Nat Rev Neurol (2019)15: 483-490. DOI: 10.1038/s41582-019-0216-y

Haanes KA, Labastida-Ramirez A, Blixt FW, Rubio-Beltran E, Dirven CM, Danser AH, Edvinsson L, MaassenVanDenBrink A. Exploration of purinergic receptors as potential anti-migraine targets using established pre-clinical migraine models. Cephalalgia (2019)39: 1421-1434. DOI:10.1177/0333102419851810

Labastida-Ramirez A, Rubio-Beltran E, Haanes KA, de VR, Dammers R, Bogers AJJC, van den Bogaerdt A, Daugherty BL, Danser AHJ, Villalon CM, MaassenVanDenBrink A. Effects of two isometheptene enantiomers in isolated human blood vessels and rat middle meningeal artery - potential antimigraine efficacy. J Headache Pain (2019) 20: 47. DOI:10.1186/s10194-019-1003-2

Haanes KA, Edvinsson L Pathophysiological Mechanisms in Migraine and the Identification of New Therapeutic Targets. CNS Drugs (2019) 33: 525-537. DOI: 10.1007/s40263-019-00630-6

Christensen ST, Johansson SE, Radziwon-Balicka A, Warfvinge K, Haanes KA, Edvinsson L (2019) MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats. PLoS One (2019) 14: e0215398. 10.1371/journal.pone.0215398

Kristiansen SB, Skovsted GF, Berchtold LA, Radziwon-Balicka A, Dreisig K, Edvinsson L, Sheykhzade M, Haanes KA Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion (2018). Scand Cardiovasc J 52: 340-343. 10.1080/14017431.2018.1552793

Frank W Blixt, Kristian A Haanes, Lena Ohlsson, Karin Dreisig Sörensen, Vadim Fedulov, Karin Warfvinge, Lars Edvinsson: MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion 2018 Experimental Eye Research 12;179:142-149. doi: 10.1016/j.exer.2018.11.003

Anders T Christiansen, Nina Sørensen, Kristian A Haanes, Frank W Blixt, Morten la Cour, Karin Warvinge, Kristian Klemp, David P. D. Woldbye^,, Jens F Kiilgaard; Neuropeptide Y treatment induces retinal vasoconstriction and causes functional and histological retinal damage in a porcine ischemia model Acta Ophthalmology 2018; 96(8):812-820. doi: 10.1111/aos.13806.

Lars Edvinsson, Kristian A Haanes, Karin Warfvinge, and Diana N. Krause: CGRP as the target of new migraine therapies: A successful translation from bench to clinic Nature Reviews Neurology 2018;14(6):338-350. doi: 10.1038/s41582-018-0003-1.

Kristian A. Haanes, Alejandro Labastida-Ramírez, Kayi Y. Chan, , René de Vries, Shook,B., Jackson,P., Zhang,J., Flores,C.M., Alexander H.J. Danser, Carlos M. Villalón and Antoinette MaassenVanDenBrink Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine. J. Headache Pain 2018; 19, 41. DOI: 10.1186/s10194-018-0867-x

Frank W Blixt, Kristian Agmund Haanes, Lena Ohlsson, Anders Tolstrup Christiansen, Karin Warfvinge, Lars Edvinsson: Increased Endothelin-1 mediated vasoconstriction after organ culture in rat and porcine ocular arteries can be suppressed with MEK/ERK1/2 inhibitors Acta Ophthalmologica 2018; DOI: 10.1111/aos.13651

Simona D Fredriksen, Kristian Agmund Haanes, Karin Warfvinge, Lars Edvinsson: Perivascular neurotransmitters: regulation of cerebral blood flow and role in primary headaches J Cereb Blood Flow Metab. 2017; DOI: 10.1177/0271678X17747188.

Sarah Brøgger Kristiansen, Majid Sheykhzade, Lars Edvinsson, Kristian Agmund Haanes: Changes in vasodilation following myocardial ischemia/reperfusion in rats. Nitric Oxide 2017;70:68-75. DOI:10.1016/j.niox.2017.09.002

Sarah Brøgger Kristiansen, Kristian Agmund Haanes, Majid Sheykhzade, Lars Edvinsson: Endothelin receptor mediated Ca2+ signaling in coronary arteries after experimentally induced ischemia/reperfusion injury in rat. J Mol Cell Cardiol 2017;111:1-9. DOI: 10.1016/j.yjmcc.2017.07.013

Stine Spray, Sara Ellinor Johansson, Aneta Radziwon-Balicka, Kristian Agmund Haanes, Karin Warfvinge, Gro Klitgaard Povlsen, Paul A.T. Kelly, Lars Edvinsson: Enhanced contractility of intraparenchymal arterioles after global cerebral ischemia in rat - new insights into the development of delayed cerebral hypoperfusion. Acta Physiologica 11/2016;, DOI:10.1111/apha.12834

Frank W. Blixt, Sara Ellinor Johansson, Leif Johnson, Kristian Agmund Haanes, Karin Warfvinge, Lars Edvinsson: Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage after Transient Global Cerebral Ischemia in Rat. PLoS ONE 06/2016; 11(6). DOI:10.1371/journal.pone.0157669

Kristian Agmund Haanes, Ka Yi Chan, Antoinette MaassenVanDenBrink: Comment on “A second trigeminal CGRP receptor: function and expression of the AMY1 receptor”. 04/2016; 3(4). DOI:10.1002/acn3.286

Kristian Agmund Haanes, Lars Schack Kruse, Helle Wulf-Johansson, Christian Christensen Stottrup, Grith Lykke Sorensen, Lars Edvinsson: Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice. Nicotine & Tobacco Research 05/2016 (18).; DOI:10.1093/ntr/ntv243

Kristian Agmund Haanes, Stine Spray, Susanne Syberg, Niklas Rye Jørgensen, Bernard Robaye, Jean-Marie Boeynaems, Lars Edvinsson: New insights on pyrimidine signalling within the arterial vasculature — Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse. Journal of Molecular and Cellular Cardiology 01/2016; 93. DOI:10.1016/j.yjmcc.2016.01.025

Cornelia Lundblad, Kristian Agmund Haanes, Gustaf Grände, Lars Edvinsson: Experimental inflammation following dural application of complete Freund’s adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage. The Journal of Headache and Pain 12/2015; 16(1). DOI:10.1186/s10194-015-0575-8

M Lukács, KA Haanes, Zs Majláth, J Tajti, L Vécsei, K Warfvinge, L Edvinsson: Dural administration of inflammatory soup or Complete Freund's Adjuvant induces activation and inflammatory response in the rat trigeminal ganglion. The Journal of Headache and Pain 12/2015; 16(1). DOI:10.1186/s10194-015-0564-y

Justyna M Kowal, Kristian A Haanes, Nynne M Christensen, Ivana Novak: Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. Cell Communication and Signaling 06/2015; 13(1). DOI:10.1186/s12964-015-0107-9

Kristian A Haanes, Lars Edvinsson: Expression and Characterization of Purinergic Receptors in Rat Middle Meningeal Artery-Potential Role in Migraine. PLoS ONE 09/2014; 9(9). DOI:10.1371/journal.pone.0108782

Kristian AHaanes, Lars Edvinsson: Characterization of the contractile P2Y14 receptor in mouse coronary and cerebral arteries. FEBS Letters 06/2014; 588(17). DOI:10.1016/j.febslet.2014.05.044

Gustaf Grände, Sieneke Labruijere, Kristian Agmund Haanes, Antoinette Maassenvandenbrink, Lars Edvinsson: Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds. The Journal of Headache and Pain 04/2014; 15(1). DOI:10.1186/1129-2377-15-22

KA Haanes, J M Kowal, G Arpino, S C Lange, Y Moriyama, PA Pedersen, I Novak: Role of vesicular nucleotide transporter VNUT (SLC17A9) in release of ATP from AR42J cells and mouse pancreatic acinar cells. Purinergic Signalling 02/2014; 10(3). DOI:10.1007/s11302-014-9406-7

Ivana Novak, Kristian A Haanes, Jing Wang: Acid-base transport in pancreas—new challenges. Frontiers in Physiology 12/2013; 4. DOI:10.3389/fphys.2013.00380

Jing Wang, Kristian A Haanes, Ivana Novak: Purinergic regulation of CFTR and Ca2+-activated Cl- channels and K+ channels in human pancreatic duct epithelium. AJP Cell Physiology 01/2013; 304(7). DOI:10.1152/ajpcell.00196.2012

Kristian A Haanes, Albrecht Schwab, Ivana Novak: The P2X7 Receptor Supports Both Life and Death in Fibrogenic Pancreatic Stellate Cells. PLoS ONE 12/2012; 7(12). DOI:10.1371/journal.pone.0051164

Ivana Novak, Jing Wang, Katrine L Henriksen, Kristian A Haanes, Simon Krabbe, Roland Nitschke, Susanne E Hede: Pancreatic Bicarbonate Secretion Involves Two Proton Pumps. Journal of Biological Chemistry 10/2010; 286(1). DOI:10.1074/jbc.M110.136382

Kristian A Haanes, Ivana Novak: ATP storage and uptake by isolated pancreatic zymogen granules. Biochemical Journal 05/2010; 429(2). DOI:10.1042/BJ20091337

Ivana Novak, Kristian A Haanes, Mette R Hansen, Simon Krabbe, Susanne E Hede: Extracellular purinergic signaling in pancreas. The Journal of Medical Investigation 01/2009; 56 Suppl(Supplement). DOI:10.2152/jmi.56.355